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Scientist II/Senior Scientist I, Solid State Chemistry

Company: Pharmacyclics
Location: Waukegan
Posted on: December 5, 2019

Job Description:

Date Posted November 24, 2019 Category Science-Chemistry Employment Type Full-time Application Deadline Open until filled Solid State Chemists at AbbVie work in cross-functional teams to support projects through all phases of development (Lead Optimization to Process Validation). In early development, they work in cross functional teams to help pick the best molecule for development, identify solid form of the API and develop scalable API isolation processes for early clinical studies. During Phase II, they work with engineers and formulation scientists to establish structure-property-performance correlations and deliver commercial API isolation processes with optimized physical properties. In the final stages of development, Solid State Chemists at AbbVie help align control strategies across API and drug product and transition isolation processes and relevant physical characterization methods to commercial manufacturing sites. Throughout development, they work with relevant teams to ensure successful regulatory submissions. In order to develop and implement robust solutions, Solid State Chemists at AbbVie use a very diverse set of experimental, analytical techniques, automation and modeling tools. The Solid-State Chemistry group is seeking a Scientist preferably with experience and some expertise in the areas of solid form development, molecular, and mathematical modeling. Basic: - Bachelors, Masters, or PhD with 8+ (BS), 5+ (MS), and 0-3 (PhD) years of experience in pharmaceutical or related industry. Preferred educational background includes but is not restricted to Physical Chemistry, Material Sciences, Pharmaceutical Sciences or Chemical Engineering. - Sound understanding of biopharmaceutical concepts to improve drug-ability of molecules through salts and cocrystals. Strong knowledge of polymorphism concepts and solid form development along with experience in analytical tools used. - Expertise in developing and deploying state of the art computational tools for physio-chemical assessment of molecules and optimization of solid forms and their properties. - Knowledge and expertise in computational chemistry, including quantum mechanics and molecular dynamics. Experience in AI/machine learning with demonstrated ability to build and integrate models. - Experience in leveraging cutting-edge automation tools and data mining/analytics techniques to probe key development questions and build robust foundational knowledge base. - Record of independently leading research for short- and long-term organizational objectives. - Excellent communication skills and demonstrated record of building lasting partnerships across functional boundaries. Key Leadership Competencies: - Builds strong relationships with peers and cross functionally with partners outside of team to enable higher performance. - Learns fast, grasps the 'essence' and can change course quickly where indicated. - Raises the bar and is never satisfied with the status quo. - Creates a learning environment, open to suggestions and experimentation for improvement. - Embraces the ideas of others, nurtures innovation and manages innovation to reality. Level will be commensurate with experience. Apply *Please mention PhdJobs to employers when

Keywords: Pharmacyclics, Waukegan , Scientist II/Senior Scientist I, Solid State Chemistry, Other , Waukegan, Illinois

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